E. Eppard, K.P. Zhernosekov, D.V. Filosofov, F. Rösch.
68Ga radiolabelling in aqueous sulutions utilizing cation exchange based post-processing for clinical application.
Nature Protocolls (2016)
P. Spang, C. Herrmann, F. Rösch.
Bifunctional gallium-68 chelators: Past, present and future
Seminars in Nulear Medicine 46/5 (2016) 373-94
Doi: 10.1053/j.semnuclmed.2016.04.003
A. Passah, M. Tripathi, S. Ballal, M.P. Yadav, R. Kumar, F. Rösch, M. Meckel, P.S. Chkraborty, C. Bal.
Evaluation of bone seeking novel radiotracer 68Ga-NO2AP-bisphosphonate for the detection of skeletal metatstasesin carcinoma breast
EJNMMI (2016)
J. Seemann, B.P. Waldron, D. Parker, F. Rösch.
DOTATOC: a novel conjugate for 68Ga labelling of TOC at ambient temperature, EJNMMI Radiopharmcy 1:4 2016
DOI 10.1186/s41181-016-0007-3
N. Pfannkuchen, M. Meckel, V. Kubicek, P. Hermann, R. Bergmann, J. Steinbach, J. Pietzsch, C.S. Bal, H.R. Kulkarni, W. Mohnike, R. P. Baum, F. Rösch.
68Ga- und 177Lu-markierte Bisphosphonate als Knochenmetastasen-Theranostika /// 68Ga- and 177Lu-labeled Bisphosphonates as Theranostic Agents for Bone Metastases
Der Nuklearmediziner, Nuk/565/15.4.2015/MPS, in press
J. Seemann, B.P. Waldron, F. Rösch, D. Parker.
Approaching 'Kit-Type' Labelling with 68Ga: The DATA Chelators.
ChemMedChem. 2015 Apr 21.
doi: 10.1002/cmdc.201500092. [Epub ahead of print]
J. Seemann, E. Eppard, B.P. Waldron, T.L. Ross, F. Rösch.
Cation exchange-based post-processing of (68)Ga-eluate: A comparison of three solvent systems for labelling of DOTATOC, NO2AP(BP) and DATA(m.).
Appl Radiat Isot. 2015 Apr;98:54-9. doi: 10.1016
O. Thews, M. Zimny, E. Eppard, M. Piel, N. Bausbacher, V. Nagel, F. Rösch.
In vitro and in vivo structure-property relationship of 68Ga-labeled Schiff base derivatives for functional myocardial pet imaging.
Mol Imaging Biol. 2014 Dec;16(6):802-12. doi: 10.1007/s11307-014-0750-3
E. Eppard, N.S. Loktionova, F. Rösch.
68Ge content quality control of 68Ge/68Ga-generator eluates and 68Ga radiopharmaceuticals – A protocol for determining the 68Ge content using thin-layer chromatography
Apl Radiat Isot 2014
E. Eppard, M. Wuttke, P.L. Nicodemus, F. Rösch.
Ethanol-Based Post-processing of Generator-Derived 68Ga Toward Kit-Type Preparation of 68Ga-Radiopharmaceuticals.
J Nucl Med. 2014 Apr 21. [Epub ahead of print]
J1 Holub, M. Meckel, V. Kubíček, F. Rösch, P. Hermann.
Gallium(III) complexes of NOTA-bis (phosphonate) conjugates as PET radiotracers for bone imaging.
Contrast Media Mol Imaging. 2014 May 6.
doi: 10.1002/cmmi.1606. [Epub ahead of print]
E. Eppard, N.S. Loktionova, F. Rösch.
Quantitative online isolation of 68Ge from 68Ge/68Ga generator eluates for purification and immediate quality control of breakthrough
Applied Radiation and Isotopes 82 (2013) 45-48
M. Meckel, M. Fellner, N. Thieme, R. Bergmann, V. Kubicek, F. Rösch.
In vivo comparison of DOTA based 68Ga-labelled bisphononates for bone imaging in non-tumour models
Nuclear Medicine and Biology (40 (2013) 823-830
A.F. Martins, M.I.M. Prata, S.P.J. Rodrigues, C.F.G.C. Geraldes, P.J. Riss, A. Amor-Coarasa, C. Burchardt, C. Kroll, F. Rösch.
Spectroscopic, radiochemical, and theoretical studies of the Ga3+-N-2hydroxyethyl piperazine-N’-2-ethanesulfonic acid (HEPES buffer) system: evidence for the formation of Ga3+- HEPES complexes in 68Ga labelling reactions
Eur J Nucl Med Mol Imaging 2013, 8 265-273
E. Eppard, N.S. Loktionova, F. Rösch.
Quantitative online isolation of 68Ge from 68Ge/68Ga generator eluates for purification and immediate quality control of breakthrough.
Appl Rad Isot 82 (2013) 45-48
F. Zoller, P.J. Riss, F.P. Montforts, D.K. Kelleher, E. Eppard, F. Rösch.
Radiolabelling and preliminary evaluation of 68Ga-tetrapyrrole derivatives as potential tracers for PET
Nuclear Medicine and Biology 40 (2013) 280–288
F. Rösch
Past, present and future of 68Ge/68Ga generators.
Appl Radiat Isot. 76 (2013) 24-30
doi:pii: S0969-8043(12)00535-0. 10.1016/j.apradiso.2012.10.012.
F. Rösch
68Ge/68Ga generators and 68Ga radiopharmaceutical chemistry on their way into a new century.
J Postgrad Med, Edu Res 47(19 (2013) 18-25
B.P. Waldron, D. Parker, C. Burchardt, D.S. Yufit, M. Zimny, F. Rösch.
Structure and stability of hexadentate complexes of ligands based on AAZTA for efficient PET labelling with gallium-68.
Chem Commun (Camb). 2013 Jan 21;49(6):579-81.
doi: 10.1039/c2cc37544c. Epub 2012 Dec 4.
E. Koumarianou, N.S. Loktionova, M. Fellner, F. Rösch, O. Thews, D. Pawlak, S.C. Archimandritis, R. Mikolajczak.
44Sc-DOTA-BN[2-14]NH(2) in comparison to 68Ga-DOTA-BN[2-14]NH2 in pre-clinical investigation. Is 44Sc a potential radionuclide for PET?
Appl Radiat Isot. 70/12 (2012) 2669-76.
doi: 10.1016/j.apradiso.2012.08.004. Epub 2012 Aug 23.
F. Rösch
Maturation of a key resource – The Germanium-68/Gallium-68 generator: Development and new insights.
Current Radiopharmaceutical 5 (2012) 202-211
P.J. Riss, C. Burchardt, F. Rösch.
A methodical 68Ga-labelling study of DO2A-(butyl-L-tyrosine)2 with cation-exchanger post-processed 68Ga: practical aspects of radiolabelling.
Contrast Media Mol Imaging. 6/6 (2011) 492-8.
F. Rösch , R.P. Baum.
Generator-based PET radiopharmaceuticals for molecular imaging of tumours: On the way to THERANOSTICS.
Dalton Transactions 40/23 (2011) 6104-6111
N.S. Loktionova, A.N. Belozub, D.V. Filosofov, K.P. Zhernosekov, T. Wagner, A. Türler, F. Rösch.
Improved column-based radiochemical processing of the generator produced 68Ga.
Applied Radiation Isotopes 69 (2011) 942-6
V. Kumar, D.K. Boddeti, S.C. Evans, F. Rösch, R. Howman-Giles.
Potential use of 68Ga-apo-transferrin as a PET imaging agent for detecting Staphylococcus aureus infection.
Nuclear Medicine and Biology 38 (2011) 393–398
M. Fellner, P.J. Riss, NS. Loktionova, KP. Zhernosekov, O. Thews, CFGC. Geraldes, Z. Kovacs, I. Lukes, F. Rösch.
Comparison of different phosphorus-containing ligands complexing 68Ga for PET-imaging of bone metabolism
Radiochimica Acta 99/1 (2011) 43-51
M. Fellner, W. Dillenburg, H.-G. Buchholz, N. Bausbacher, M. Schreckenberger, F. Renz, F. Rösch, O. Thews.
Assessing p-glycoprotein (Pgp) activity in vivo utilizing 68Ga-Schiff base complexes
Mol Imaging Biol. 13(5) (2011) 985-94
P.J. Riss, N. Hanik, F. Rösch.
Studies towards the development of lipophilic bifunctional N3S3 chelators for 68Ga
Radiochimica Acta 98/8 (2010) 519-523
F. Zoller, P.J. Riss, F.-P. Montforts, F. Rösch.
Efficient post-processing of aqueous generator eluates facilitates 68Ga-labelling under anhydrous conditions
Radiochimica Acta 98/3 (2010) 157-160
F. Rösch, P.J. Riss.
The Renaissance of the 68Ge/68Ga radionuclide generator initiates new developments in 68Ga
radiopharmaceutical chemistry
Curr Top Med Chem. 10/16 (2010) 1633-68
O. Thews, W. Dillenburg, M. Fellner, H.-G. Buchholz, N. Bausbacher, M. Schreckenberger, F. Rösch.
Activation of P-glycoprotein (Pgp)-mediated drug efflux by extracellular acidosis: in vivo imaging with 68Ga-labelled PET tracer
Eur J Nucl Med Mol Imaging. 37(10) (2010) 1935-42
J. Notni, P. Hermann, J. Havlíčková, J. Kotek, V. Kubíček, J. Plutnar, N. Loktionova, P.J. Riss, F. Rösch, I. Lukeš.
A triazacyclononane-based bifunctional phosphinate ligand for the preparation of multimeric 68Ga tracers for Positron Emission Tomography
Chemistry. 16/24 (2010) 7174-85
F. Rösch
Impurity in 68Ga-peptide preparation using processed generator eluate
J Nucl Med 51 (2010) 496
M. Fellner, R.P. Baum, J.A. Peters, I. Lukeš, P. Hermann, V. Prasad, F. Rösch.
PET/CT imaging of osteoblastic bone metastases with 68Ga-bisphosponates - first in human study
Eur J Nucl Med Mol Imaging 37(4) (2010) 834
C. Burchardt, P.J. Riss, F. Zoller, S. Maschauer,O. Prante, T. Kuwert, F. Rösch.
[68Ga]Ga-DO(2)A-(OBu-l-tyr)2: Synthesis, 68Ga-radiolabeling and in vitro studies of a novel 68Ga-DO2A-tyrosine conjugate as potential
tumor tracer for PET
Bioorg Med Chem Lett 19(13) (2009) 3498-501
P.J. Riss, C. Kroll, V. Nagel, F. Rösch.
NODAPA-OH and NODAPA-(NCS)n: Synthesis, 68Ga-radiolabelling and in vitro characterisation of novel versatile bifunctional chelators for
molecular imaging
Bioorg Med Chem Let. 18 (2008) 5364–5367
M. Asti, G. De Pietria, A. Fraternalia, E. Grassib, R. Sghedonib, F. Fioronib, F. Rösch, A. Versaria, D. Salvoa.
Validation of 68Ge/68Ga generator processing by chemical purification for routine clinical application of 68Ga-DOTATOC
Nucl Med Biol 35 (2008) 721-724
KP. Zhernosekov, DV. Filosofov, R.P.Baum, P. Aschoff, H. Bihl, AA. Razbash, M. Jahn, M. Jennewein, Rösch.
Processing of generator-produced 68Ga for medical application
J Nucl Med. 48 (2007) 1741-1748
F. Rösch, KP. Zhernosekov, DV. Filosofov, M. Jahn, M. Jennewein.
The status and the potential of new radionuclide generators providing positron emitters to synthesise new targeting vectors for PET
IAEA-CN-130/068, 2006
K. Zhernosekov, P. Aschoff, D. Filosofov, M. Jahn, M. Jennewein, H.J. Adrian, H. Bihl, F. Rösch.
Visualisation of a somatostatin receptor-expressing tumour with 67Ga-DOTATOC SPECT
Eur J Nucl Med Mol Imaging 32 (2005) 1129
H.J. Wester, J. Brockmann, F. Rösch, B. Stolz, W. Wutz, H. Herzog, P.M. Smith-Jones, C. Bruns, G. Stöcklin.
Quantitative in vivo uptake kinetics of 18F-octreotide measured by PET: A comparison with 86Y-DTPA-octreotide and 68Ga-DFO-octreotide
in tumor bearing rats
Nucl Med Biol, 24 (1997) 275-286
J. Brockmann, F. Rösch.
Labelling of small peptides with yttrium and gallium via a new DOTA-derivative or DFO using different disuccinimidylic esters as linker
J Lab Compf Radiopharm, 37 (1995) 516-518
AF. Novgorodov, F. Rösch, A. Szielinski, R. Misak, Kolachkovski, G.J. Beyer, K. Schomäcker.
Simple thermochromatographic separation of 67Ga from metallic zinc targets
Isotopenpraxis, 26 /4/ (1990) 11-13
|
